منابع مشابه
Mouse Thalamic Differentiation: Gli-Dependent Pattern and Gli-Independent Prepattern
Sonic hedgehog (Shh) signaling is essential for thalamic development. The Gli transcription factors act downstream of Shh - while Gli2 is the major activator (GliA), Gli3 acts primarily as a repressor (GliR). The thalamus is remarkable among dorsal structures because of its proximity to the mid-diencephalic organizer, a unique dorsal Shh source. This lends complexity to the interactions between...
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This article offers a critical discussion of Pocock's analysis of the relationship between Gibbon and Voltaire, and particularly the extent to which Decline and Fall was inspired by Voltaire's Essai sur les moeurs. It shows that "Momigliano's hypothesis" about the divorce of philosophy and erudition and their reconciliation in Gibbon was initially a commentary by Momigliano on Voltaire's histor...
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Description Protein: Human GLI2 was originally identified as a Tax-helper protein (THP) that binds to Tax-responsive element in the long terminal repeat of the human T-cell leukemia virus (Tanimura et al., 1998). However, when compared to orthologous GLI2 genes from different species, the human mRNAs lacked a part of the 5' region encoding the evolutionarily conserved Nterminus of GLI2. Roessle...
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Gli zinc-finger proteins are transcription factors involved in the intracellular signal transduction controlled by the Hedgehog family of secreted molecules. They are frequently mutated in human congenital malformations, and their abnormal regulation leads to tumorigenesis. Genetic studies in several model systems indicate that their activity is tightly regulated by Hedgehog signaling through v...
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Augmin-ting the central spindle T he augmin complex generates new micro-tubules in anaphase to build the central spindle and complete cytokinesis, Uehara and Goshima report. The central spindle forms between segregating chromosomes in anaphase and is required for the subsequent cleavage of cells into two daughters. Whether this structure is formed purely by microtubules recycled from the metaph...
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ژورنال
عنوان ژورنال: Studi Francesi
سال: 2022
ISSN: ['2421-5856', '0039-2944']
DOI: https://doi.org/10.4000/studifrancesi.51293